Editing Windows Install (section)

=== Pre-compiled Open-Source PyMOL ===

Pre-compiled Open-Source PyMOL is available free from [https://www.cgohlke.com/ Christoph Gohlke of the Laboratory for Fluorescence Dynamics, University of California, Irvine].

# Install the latest version of Python 3 for Windows (e.g., by going to http://www.python.org/downloads/ and choosing the x64 EXE installer). Use the standard options, which should mean that the installation directory is most likely C:\Users\<Your Username>\AppData\Local\Programs\Python\Python38). Make sure the option to add environment variables is selected or add the folder of python.exe to system PATH.
# Install [https://support.microsoft.com/en-us/help/2977003/the-latest-supported-visual-c-downloads the current Microsoft Visual C++ Redistributable for Visual Studio 2015, 2017 and 2019]. Otherwise the installed PyMOL binary may fail to run (without any error message!).
## Have a look in "Add/Remove" programs if it's installed already
# Download the [https://github.com/cgohlke/pymol-open-source-wheels/ appropriate wheel files], along with all requirement wheel files ([https://github.com/cgohlke/numpy-mkl-wheels/ Numpy+MKL]) into a single file directory, e.g., <code>C:\Users\<Your Username>\Downloads</code>
# Example of filenames 2023-01-12
## pymol_launcher-2.5-cp311-cp311-win_amd64.whl
## pymol-2.6.0a0-cp311-cp311-win_amd64.whl
## numpy-1.22.4+mkl-cp311-cp311-win_amd64.whl

Navigate to the installation directory in a CMD window (Not PowerShell!) <source lang = python>cd C:\Users\<Your Username>\Downloads</source> (or where ever you put the files) and begin the installation using the command: ("%CD%" only works in CMD) 
<source lang = python>
python -m pip pmw
python -m pip install --no-index --find-links="%CD%" pymol_launcher-2.5-cp311-cp311-win_amd64.whl
where.exe pymol
pymol
</source>

PyMOL.exe should now be in C:\Users\<Your Username>\AppData\Local\Programs\Python

To use the newer single-window Qt interface, also install the optional PyQt5 dependency for your Python installation: 
<source lang=python>
python -m pip install pyqt5
</source>

To update PyMOL update the files in the PyMOL install directory and run: 
<source lang = python>
pip install --upgrade --no-deps pymol.whl
</source> 
where <code>pymol.whl</code> is replaced by the PyMOL wheel file name (not the launcher, the launcher should not require updating).